Immunogen
Synthesized peptide derived from human NCS1 AA range: 3-53
Specificity
This antibody detects endogenous levels of NCS1 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene is a member of the neuronal calcium sensor gene family, which encode calcium-binding proteins expressed predominantly in neurons. The protein encoded by this gene regulates G protein-coupled receptor phosphorylation in a calcium-dependent manner and can substitute for calmodulin. The protein is associated with secretory granules and modulates synaptic transmission and synaptic plasticity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
Function
function:Neuronal calcium sensor, regulator of G protein-coupled receptor phosphorylation in a calcium dependent manner. Directly regulates GRK1 (RHOK), but not GRK2 to GRK5. Can substitute for calmodulin.,miscellaneous:Binds 3 calcium ions via the second, third and fourth EF-hand.,similarity:Belongs to the recoverin family.,similarity:Contains 4 EF-hand domains.,subcellular location:Associated with Golgi stacks. Post-synaptic densities of dendrites, and in the pre-synaptic nerve terminal at neuromuscular junctions.,subunit:Interacts with KCND2.,
Human protein sequence Database
P62166
Mouse protein sequence database
Q8BNY6
Rat protein sequence database
P62168
Cellular localization
Golgi apparatus . Cell junction, synapse, postsynaptic density . Cytoplasm, perinuclear region . Cytoplasm . Cell membrane ; Peripheral membrane protein. Membrane ; Lipid-anchor . Associated with Golgi stacks. Post-synaptic densities of dendrites, and in the pre-synaptic nerve terminal at neuromuscular junctions. .
Contract Us
Follow Us
Location： 
Specification
成功添加到购物车