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TFB2M rabbit pAb

Refer to | for labeled antibodies

Specification

BYab-11636

  • 50UL $180 100UL $255
  • Delivery: In Stock

Product introduction Experimental scheme Citation Related products

Product introduction>

Host
Reactiveness
Use
Molecular weight (DA)
Immunogen
Synthesized peptide derived from human TFB2M AA range: 192-242
Specificity
This antibody detects endogenous levels of TFB2M at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration
1 mg/ml
Background
Function
function:S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity. Compared to TFB1M, it activates transcription of mitochondrial DNA more efficiently, while it has less methyltransferase activity.,induction:By the nuclear respiratory factors NRF1 and NRF2/GABPB2 and PGC-1 coactivators.,similarity:Belongs to the rRNA adenine N(6)-methyltransferase family. KsgA subfamily.,subunit:Interacts with mitochondrial RNA polymerase POLRMT. Interacts with TFAM.,tissue specificity:Ubiquitously expressed.,
Gene Name
TFB2M NS5ATP5
Protein name
TFB2M
Abbreviation
TFB2M
Other name
Fields
Human gene ID
64216
Human protein sequence Database
Q9H5Q4
Mouse gene ID
15278
Mouse protein sequence database
Q3TL26
Rat gene ID
289307
Rat protein sequence database
Q5U2T7
Cellular localization
Mitochondrion.
Tissue expression
Ubiquitously expressed.
Storage
-20°C/1 year

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TFB2M rabbit pAb

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