Immunogen
Synthesized peptide derived from human C99L2 AA range: 204-254
Specificity
This antibody detects endogenous levels of C99L2 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a cell-surface protein that is similar to CD99. A similar protein in mouse functions as an adhesion molecule during leukocyte extravasation. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010],
Function
function:May function as a homophilic adhesion molecule. Functions in leukocyte-endothelial cell interactions during leukocyte extravasation, and in particular, at the diapedesis step. Does not seem to be involved in docking of leukocytes to the vessel wall or in lymphocyte diapedesis.,PTM:O-glycosylated.,similarity:Belongs to the CD99 family.,tissue specificity:Expressed in brain, heart, lung, liver, spleen, kidney, stomach, small intestine, skeletal muscle, ovary, thymus, testis and uterus. Lower expression seen in thymus. Expressed in E18 uterus and placenta.,
Gene Name
CD99L2 MIC2L1 UNQ1964/PRO4486
Fields
>>Cell adhesion molecules;>>Leukocyte transendothelial migration
Human protein sequence Database
Q8TCZ2
Mouse protein sequence database
Q8BIF0
Rat protein sequence database
Q8R1R5
Cellular localization
Cell membrane ; Single-pass type I membrane protein ; Extracellular side . Cell junction .
Tissue expression
Expressed in many tissues, with low expression in thymus.