Immunogen
Synthesized peptide derived from human IFFO1 AA range: 387-437
Specificity
This antibody detects endogenous levels of IFFO1 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene is a member of the intermediate filament family. Intermediate filaments are proteins which are primordial components of the cytoskeleton and nuclear envelope. The proteins encoded by the members of this gene family are evolutionarily and structurally related but have limited sequence homology, with the exception of the central rod domain. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010],
Function
similarity:Belongs to the intermediate filament family.,tissue specificity:Ubiquitously expressed.,
Human protein sequence Database
Q0D2I5
Mouse protein sequence database
Q8BXL9
Rat protein sequence database
Cellular localization
Nucleus . Nucleus, nucleoplasm . Nucleus inner membrane . Nucleus matrix . Mainly soluble, the remaining is localized in the nuclear matrix (PubMed:31548606). Localized at double-strand break (DSB) sites near the lamina and nuclear matrix structures (PubMed:31548606). .
Tissue expression
Ubiquitously expressed.
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