Immunogen
Synthesized peptide derived from human MTCH1 AA range: 235-285
Specificity
This antibody detects endogenous levels of MTCH1 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a member of the mitochondrial carrier family. The encoded protein is localized to the mitochondrion inner membrane and induces apoptosis independent of the proapoptotic proteins Bax and Bak. Pseudogenes on chromosomes 6 and 11 have been identified for this gene. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Oct 2012],
Function
function:Potential mitochondrial transporter. May play a role in apoptosis.,similarity:Belongs to the mitochondrial carrier family.,similarity:Contains 2 Solcar repeats.,subunit:Interacts with PSEN1.,tissue specificity:Widely expressed with a predominant expression in brain.,
Gene Name
MTCH1 PSAP CGI-64 UNQ1871/PRO4314
Human protein sequence Database
Q9NZJ7
Mouse protein sequence database
Q791T5
Rat protein sequence database
Cellular localization
Mitochondrion outer membrane ; Multi-pass membrane protein .
Tissue expression
Widely expressed with a predominant expression in brain.
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