Immunogen
Synthesized peptide derived from human RN169 AA range: 123-173
Specificity
This antibody detects endogenous levels of RN169 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
similarity:Contains 1 RING-type zinc finger.,
Gene Name
RNF169 KIAA1991
Human protein sequence Database
Q8NCN4
Mouse protein sequence database
E9Q7F2
Rat protein sequence database
Cellular localization
Chromosome . Nucleus, nucleoplasm . Localizes to sites of double-strand breaks (DSBs) following DNA damage. Recruited to DSBs via recognition of RNF168-dependent ubiquitin products. .