Immunogen
Synthesized peptide derived from human AFAF AA range: 223-273
Specificity
This antibody detects endogenous levels of AFAF at Human
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
function:Involved in acrosome biogenesis.,tissue specificity:Isoform 1 highly expressed in testis. Isoform 2 is expressed at low levels in skin and blood.,
Human protein sequence Database
Q9NQ60
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Cytoplasmic vesicle, secretory vesicle, acrosome membrane ; Single-pass type I membrane protein . Cytoplasmic vesicle, secretory vesicle, acrosome inner membrane ; Single-pass type I membrane protein . Cytoplasmic vesicle, secretory vesicle, acrosome outer membrane ; Single-pass type I membrane protein . In the anterior acrosome region, enriched on the inner acrosomal membrane but minimal on the outer acrosomal membrane; in contrast in the posterior acrosome region enriched on both the inner and outer acrosomal membranes. .
Tissue expression
Isoform 1 is highly expressed in testis. Isoform 2 is expressed at low levels in skin and blood.
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