Immunogen
Synthesized peptide derived from human SAMN1 AA range: 316-366
Specificity
This antibody detects endogenous levels of SAMN1 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
SAMSN1 is a member of a novel gene family of putative adaptors and scaffold proteins containing SH3 and SAM (sterile alpha motif) domains (Claudio et al., 2001 [PubMed 11536050]).[supplied by OMIM, Mar 2008],
Function
similarity:Contains 1 SAM (sterile alpha motif) domain.,similarity:Contains 1 SH3 domain.,
Human protein sequence Database
Q9NSI8
Mouse protein sequence database
P57725
Rat protein sequence database
Cellular localization
Nucleus . Cytoplasm . Cell projection, ruffle . Shuttles between cytoplasm and nucleus. Colocalizes with the actin cytoskeleton and actin-rich membrane ruffles (By similarity). .
Tissue expression
Detected in peripheral blood B-cells (at protein level). Detected in spleen, liver and peripheral blood.