Immunogen
Synthesized peptide derived from human GDC AA range: 241-291
Specificity
This antibody detects endogenous levels of GDC at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a protein that contains three tandemly repeated mitochondrial carrier protein domains. The encoded protein is localized in the inner membrane and facilitates the rapid transport and exchange of molecules between the cytosol and the mitochondrial matrix space. This gene has a possible role in Graves' disease. [provided by RefSeq, Jul 2008],
Function
disease:Possible role in Graves disease. This protein is recognized by IgG from patients with active Graves disease.,function:Required for the accumulation of coenzyme A in the mitochondrial matrix.,similarity:Belongs to the mitochondrial carrier family.,similarity:Contains 3 Solcar repeats.,
Human protein sequence Database
P16260
Mouse protein sequence database
Q8C0K5
Rat protein sequence database
P16261
Cellular localization
Mitochondrion inner membrane ; Multi-pass membrane protein .