Immunogen
Synthesized peptide derived from human FMT AA range: 115-165
Specificity
This antibody detects endogenous levels of FMT at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
The protein encoded by this nuclear gene localizes to the mitochondrion, where it catalyzes the formylation of methionyl-tRNA. [provided by RefSeq, Jun 2011],
Function
catalytic activity:10-formyltetrahydrofolate + L-methionyl-tRNA(fMet) + H(2)O = tetrahydrofolate + N-formylmethionyl-tRNA(fMet).,domain:Composed of an N- and a C-terminal domain. The N-terminal domain carries the tetrahydrofolate (THF)-binding site and the C-terminal domain is presumably involved in positioning the Met-tRNA substrate for the formylation reaction.,function:Formylates methionyl-tRNA in mitochondria. A single tRNA(Met) gene gives rise to both an initiator and an elongator species via an unknown mechanism.,similarity:Belongs to the fmt family.,
Fields
>>One carbon pool by folate;>>Aminoacyl-tRNA biosynthesis;>>Metabolic pathways
Human protein sequence Database
Q96DP5
Mouse protein sequence database
Q9D799
Rat protein sequence database
Q5I0C5
Cellular localization
Mitochondrion .
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