Immunogen
Synthesized peptide derived from human BIN3 AA range: 184-234
Specificity
This antibody detects endogenous levels of BIN3 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
The product of this gene is a member of the BAR domain protein family. The encoded protein is comprised solely of a BAR domain which is predicted to form coiled-coil structures and proposed to mediate dimerization, sense and induce membrane curvature, and bind small GTPases. BAR domain proteins have been implicated in endocytosis, intracellular transport, and a diverse set of other processes. [provided by RefSeq, Jul 2008],
Function
function:Involved in cytokinesis and septation where it has a role in the localization of F-actin.,similarity:Contains 1 BAR domain.,tissue specificity:Ubiquitously expressed except in brain.,
Human protein sequence Database
Q9NQY0
Mouse protein sequence database
Q9JI08
Rat protein sequence database
Q68FW8
Cellular localization
Cytoplasm, cytoskeleton.
Tissue expression
Ubiquitously expressed except in brain.