Immunogen
Synthesized peptide derived from human LMOD2 AA range: 279-329
Specificity
This antibody detects endogenous levels of LMOD2 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
function:May block the elongation and depolymerization of the actin filaments at the pointed end.,sequence caution:Translation N-terminally shortened.,similarity:Belongs to the tropomodulin family.,similarity:Contains 1 WH2 domain.,subunit:Able to bind to tropomyosin.,tissue specificity:Specifically expressed in heart and skeletal muscles. Not expressed in other tissues.,
Human protein sequence Database
Q6P5Q4
Mouse protein sequence database
Q3UHZ5
Rat protein sequence database
A1A5Q0
Cellular localization
Cytoplasm, myofibril, sarcomere . Cytoplasm, myofibril . Cytoplasm, myofibril, sarcomere, M line . Cytoplasm, cytoskeleton . Colocalizes with actin filaments in sarcomeres. Detected close to the M line. .
Tissue expression
Specifically expressed in heart and skeletal muscles, with higher levels in heart (at protein level). Not expressed in other tissues.