Immunogen
Synthesized peptide derived from human SASH1 AA range: 373-423
Specificity
This antibody detects endogenous levels of SASH1 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
function:May have a role in a signaling pathway. Could act as a tumor suppressor.,similarity:Contains 1 SH3 domain.,similarity:Contains 2 SAM (sterile alpha motif) domains.,tissue specificity:Expressed ubiquitously, with highest levels in lung, placenta, spleen and thymus. Down-regulated in the majority (74%) of breast tumors in comparison with corresponding normal breast epithelial tissues.,
Gene Name
SASH1 KIAA0790 PEPE1
Human protein sequence Database
O94885
Mouse protein sequence database
P59808
Rat protein sequence database
Cellular localization
Cytoplasm .
Tissue expression
Expressed ubiquitously, with highest levels in lung, placenta, spleen and thymus. Down-regulated in the majority (74%) of breast tumors in comparison with corresponding normal breast epithelial tissues. Expressed in the epidermis, epidermal keratinocytes, dermal fibroblasts and melanocytes (PubMed:23333244, PubMed:26203640).
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