Immunogen
Synthesized peptide derived from human ATCAY AA range: 69-119
Specificity
This antibody detects endogenous levels of ATCAY at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a neuron-restricted protein that contains a CRAL-TRIO motif common to proteins that bind small lipophilic molecules. Mutations in this gene are associated with cerebellar ataxia, Cayman type. [provided by RefSeq, Jul 2008],
Function
disease:Defects in ATCAY are the cause of cerebellar ataxia, cayman type (ATCAY) [MIM:601238]. ATCAY is found in a population isolate on Grand Cayman Island and causes a marked psychomotor retardation and prominent nonprogressive cerebellar dysfunction including nystagmus, intention tremor, dysarthria, and wide-based ataxic gait. Hypotonia is present from early childhood.,domain:The CRAL-TRIO domain is known to bind small hydrophobic molecules.,similarity:Contains 1 CRAL-TRIO domain.,
Human protein sequence Database
Q86WG3
Mouse protein sequence database
Q8BHE3
Rat protein sequence database
Q1M168
Cellular localization
Cell projection, axon . Cell projection, dendrite . Cell junction, synapse, presynapse . Mitochondrion . Cell projection, growth cone . Cytoplasm .
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