Immunogen
Synthesized peptide derived from human GSTK1 AA range: 138-188
Specificity
This antibody detects endogenous levels of GSTK1 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a member of the kappa class of the glutathione transferase superfamily of enzymes that function in cellular detoxification. The encoded protein is localized to the peroxisome and catalyzes the conjugation of glutathione to a wide range of hydrophobic substates facilitating the removal of these compounds from cells. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2009],
Function
catalytic activity:RX + glutathione = HX + R-S-glutathione.,function:Significant glutathione conjugating activity is found only with the model substrate, 1-chloro-2,4-dinitrobenzene (CDNB).,similarity:Belongs to the GST superfamily. Kappa family.,subunit:Homodimer.,tissue specificity:Ubiquitous.,
Fields
>>Glutathione metabolism;>>Metabolism of xenobiotics by cytochrome P450;>>Drug metabolism - cytochrome P450;>>Metabolic pathways;>>Peroxisome;>>Chemical carcinogenesis - DNA adducts
Human protein sequence Database
Q9Y2Q3
Mouse protein sequence database
Q9DCM2
Rat protein sequence database
P24473
Cellular localization
Peroxisome .
Tissue expression
Ubiquitous.
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