Immunogen
Synthesized peptide derived from human ARH40 AA range: 1261-1311
Specificity
This antibody detects endogenous levels of ARH40 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a protein similar to guanosine nucleotide exchange factors for Rho GTPases. The encoded protein contains in its C-terminus a GEF domain involved in exchange activity and a pleckstrin homology domain. Alternatively spliced transcripts that encode different proteins have been described. [provided by RefSeq, Mar 2014],
Function
function:May act as a guanine nucleotide exchange factor (GEF).,similarity:Contains 1 DH (DBL-homology) domain.,similarity:Contains 1 PH domain.,subcellular location:Concentrated in the perinuclear region.,tissue specificity:Expressed at higher level in the central nervous system and skeletal muscle and greater abundance in fetal than adult brain (at protein level).,
Human protein sequence Database
Q8TER5
Mouse protein sequence database
Q3UPH7
Rat protein sequence database
Cellular localization
Cytoplasm . Concentrated in the perinuclear region.
Tissue expression
Expressed at higher level in the central nervous system and skeletal muscle and greater abundance in fetal than adult brain (at protein level).