Immunogen
Synthesized peptide derived from human WIPF3 AA range: 66-116
Specificity
This antibody detects endogenous levels of WIPF3 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
domain:The KLKR motif is essential for G-actin binding and for actin polymerization.,domain:The profilin-binding motif has been implicated in the interaction with profilin and SH3 domains.,domain:The WH2 domain is found in a number of putative actin-binding proteins.,function:May be a regulator of cytoskeletal organization. May have a role in spermatogenesis.,similarity:Belongs to the verprolin family.,similarity:Contains 1 WH2 domain.,subcellular location:In hippocampal neurons colocalizes with WASL in the cell body, axons and the growth cone.,subunit:Interacts with WASL, and monomeric and filamentous actin.,
Fields
>>Endocytosis;>>Pathogenic Escherichia coli infection;>>Yersinia infection
Human protein sequence Database
A6NGB9
Mouse protein sequence database
P0C7L0
Rat protein sequence database
Q9Z0G8
Cellular localization
Cytoplasm. In hippocampal neurons colocalizes with WASL in the cell body, axons and the growth cone. .
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