Immunogen
Synthesized peptide derived from human TEKT2 AA range: 224-274
Specificity
This antibody detects endogenous levels of TEKT2 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene product belongs to the tektin family of proteins. Tektins comprise a family of filament-forming proteins that are coassembled with tubulins to form ciliary and flagellar microtubules. This gene is expressed in the testis and its protein is localized to the flagella of the sperms, indicating that it may play a role in spermatogenesis. [provided by RefSeq, Jul 2008],
Function
function:Structural component of ciliary and flagellar microtubules. Plays a key role in the assembly or attachment of the inner dynein arm to microtubules in sperm flagella and tracheal cilia. Forms filamentous polymers in the walls of ciliary and flagellar microtubules.,similarity:Belongs to the tektin family.,subcellular location:In sperm, observed in a discontinuous punctate pattern in the flagellum and in the postacrosomal head region.,tissue specificity:Expressed at high levels in testis, trachea and fetal lung, and at lower levels in ovary, pituitary, adult lung, fetal brain and fetal kidney.,
Human protein sequence Database
Q9UIF3
Mouse protein sequence database
Q922G7
Rat protein sequence database
Q6AYM2
Cellular localization
Cytoplasm, cytoskeleton, cilium axoneme . Cytoplasm, cytoskeleton, flagellum axoneme . Cytoplasm, cytoskeleton, microtubule organizing center . Colocalized with CCDC172 at the perinuclear region. .
Tissue expression
Expressed at high levels in testis, trachea and fetal lung, and at lower levels in ovary, pituitary, adult lung, fetal brain and fetal kidney.
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