Immunogen
Synthesized peptide derived from human MRI AA range: 40-90
Specificity
This antibody detects endogenous levels of MRI at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
function:May act as a regulator of proteasome.,
Human protein sequence Database
Q9BWK5
Mouse protein sequence database
Q8BHZ5
Rat protein sequence database
Q6AYH4
Cellular localization
[Isoform 1]: Cytoplasm . Nucleus . Chromosome . Nuclear localization may depend upon interaction with XRCC5/Ku80 and XRCC6/Ku70 heterodimer (PubMed:24610814). Localizes to DNA damage sites (PubMed:27063109). .; [Isoform 3]: Cytoplasm . Some nuclear localization may be due to passive diffusion. .; [Isoform 4]: Cytoplasm . Nucleus . Nuclear localization may depend upon interaction with XRCC5/Ku80 and XRCC6/Ku70 heterodimer and increases upon etoposide treatment. .