Immunogen
Synthesized peptide derived from human FBX17 AA range: 61-111
Specificity
This antibody detects endogenous levels of FBX17 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a member of the F-box protein family which is characterized by the F-box motif. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it contains an F-box domain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],
Function
function:Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.,similarity:Contains 1 F-box domain.,similarity:Contains 1 FBA (F-box associated) domain.,subunit:Directly interacts with SKP1A and CUL1.,tissue specificity:Expressed in heart, skeletal muscle, liver and kidney. Expressed at lower levels in spleen and brain.,
Gene Name
FBXO17 FBG4 FBX17 FBX26 FBXO26
Human protein sequence Database
Q96EF6
Mouse protein sequence database
Q9QZM8
Rat protein sequence database
Q6AY27
Cellular localization
SCF ubiquitin ligase complex,
Tissue expression
Expressed in heart, skeletal muscle, liver and kidney. Expressed at lower levels in spleen and brain.
Contract Us
Follow Us
Location： 
Specification
成功添加到购物车