Immunogen
Synthesized peptide derived from human LY65C AA range: 66-116
Specificity
This antibody detects endogenous levels of LY65C at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
LY6G5C belongs to a cluster of leukocyte antigen-6 (LY6) genes located in the major histocompatibility complex (MHC) class III region on chromosome 6. Members of the LY6 superfamily typically contain 70 to 80 amino acids, including 8 to 10 cysteines. Most LY6 proteins are attached to the cell surface by a glycosylphosphatidylinositol (GPI) anchor that is directly involved in signal transduction (Mallya et al., 2002 [PubMed 12079290]).[supplied by OMIM, Mar 2008],
Function
caution:It is uncertain whether Met-1 or Met-4 is the initiator.,function:May have a role in hematopoietic cell differentiation.,PTM:N-glycosylated.,similarity:Contains 1 UPAR/Ly6 domain.,subunit:Forms oligomers.,tissue specificity:Detected in T-cell lines and fetal and adult lung.,
Gene Name
LY6G5C C6orf20 G5C NG33
Human protein sequence Database
Q5SRR4
Mouse protein sequence database
Q8K1T5
Rat protein sequence database
Q8CHN2
Cellular localization
Secreted .
Tissue expression
Detected in T-cell lines and fetal and adult lung.
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