Immunogen
Synthesized peptide derived from human GPN1 AA range: 24-74
Specificity
This antibody detects endogenous levels of GPN1 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a guanosine triphosphatase enzyme. The encoded protein may play a role in DNA repair and may function in activation of transcription. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2009],
Function
caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,function:Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding protein, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation. May be involved in nuclear localization of XPA.,similarity:Belongs to the GPN-loop GTPase family.,subunit:Tightly associated with the RNA polymerase II complex. Interacts with XPA.,tissue specificity:Expressed ubiquitously.,
Gene Name
GPN1 MBDIN XAB1 HUSSY-23
Human protein sequence Database
Q9HCN4
Mouse protein sequence database
Q8VCE2
Rat protein sequence database
Cellular localization
Cytoplasm . Nucleus . Shuttles between the nucleus and the cytoplasm. .
Tissue expression
Expressed ubiquitously.
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