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CMBL rabbit pAb

Refer to | for labeled antibodies

Specification

BYab-12393

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Product introduction>

Host
Reactiveness
Use
Molecular weight (DA)
Immunogen
Synthesized peptide derived from human CMBL AA range: 136-186
Specificity
This antibody detects endogenous levels of CMBL at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration
1 mg/ml
Background
CMBL (EC 3.1.1.45) is a cysteine hydrolase of the dienelactone hydrolase family that is highly expressed in liver cytosol. CMBL preferentially cleaves cyclic esters, and it activates medoxomil-ester prodrugs in which the medoxomil moiety is linked to an oxygen atom (Ishizuka et al., 2010 [PubMed 20177059]).[supplied by OMIM, Apr 2010],
Function
similarity:Belongs to the dienelactone hydrolase family.,
Gene Name
CMBL
Protein name
CMBL
Abbreviation
CMBL
Other name
Fields
>>Metabolic pathways
Human gene ID
134147
Human protein sequence Database
Q96DG6
Mouse gene ID
69574
Mouse protein sequence database
Q8R1G2
Rat gene ID
310201
Rat protein sequence database
Q7TP52
Cellular localization
Cytoplasm, cytosol .
Tissue expression
Widely expressed, with highest levels in liver, followed by kidney, small intestine and colon. Present in liver and intestine (at protein level).
Storage
-20°C/1 year

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CMBL rabbit pAb

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