Immunogen
Synthesized peptide derived from human ACBG1 AA range: 496-546
Specificity
This antibody detects endogenous levels of ACBG1 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
The protein encoded by this gene possesses long-chain acyl-CoA synthetase activity. It is thought to play a central role in brain very long-chain fatty acids metabolism and myelinogenesis. [provided by RefSeq, Jul 2008],
Function
catalytic activity:ATP + a long-chain carboxylic acid + CoA = AMP + diphosphate + an acyl-CoA.,function:Mediates activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Able to activate long-chain fatty acids. Also able to activate very long-chain fatty acids; however, the relevance of such activity is unclear in vivo. Can activate diverse saturated, monosaturated and polyunsaturated fatty acids.,similarity:Belongs to the ATP-dependent AMP-binding enzyme family. Bubblegum subfamily.,tissue specificity:Expressed primarily in brain. Expressed at lower level in testis and adrenal gland. Present in all regions of brain except pituitary.,
Gene Name
ACSBG1 BGM KIAA0631 LPD
Fields
>>Fatty acid biosynthesis;>>Fatty acid degradation;>>Metabolic pathways;>>Fatty acid metabolism;>>PPAR signaling pathway;>>Adipocytokine signaling pathway
Human protein sequence Database
Q96GR2
Mouse protein sequence database
Q99PU5
Rat protein sequence database
Q924N5
Cellular localization
Cytoplasm . Cytoplasmic vesicle . Microsome . Endoplasmic reticulum . Cell membrane .
Tissue expression
Expressed primarily in brain. Expressed at lower level in testis and adrenal gland. Present in all regions of brain except pituitary.
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