Immunogen
Synthesized peptide derived from human RBM3 AA range: 69-119
Specificity
This antibody detects endogenous levels of RBM3 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene is a member of the glycine-rich RNA-binding protein family and encodes a protein with one RNA recognition motif (RRM) domain. Expression of this gene is induced by cold shock and low oxygen tension. A pseudogene exists on chromosome 1. Multiple alternatively spliced transcript variants that are predicted to encode different isoforms have been characterized although some of these variants fit nonsense-mediated decay (NMD) criteria. [provided by RefSeq, Jul 2008],
Function
PTM:Arg-105 is dimethylated, probably to asymmetric dimethylarginine.,similarity:Contains 1 RRM (RNA recognition motif) domain.,
Human protein sequence Database
P98179
Mouse protein sequence database
O89086
Rat protein sequence database
Q925G0
Cellular localization
Nucleus . Cytoplasm . Cell projection, dendrite . Localizes in mRNA granules in dentrites. .