Immunogen
Synthesized peptide derived from human USP34
Specificity
This antibody detects endogenous levels of USP34 at Human, Mouse,Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, and 0.59% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
catalytic activity:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol.,function:Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquinated proteins.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the peptidase C19 family.,tissue specificity:Expressed in brain at low level.,
Gene Name
USP34 KIAA0570 KIAA0729
Other name
Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.4.19.12) (Deubiquitinating enzyme 34) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34)
Human protein sequence Database
Q70CQ2
Mouse protein sequence database
Q6ZQ93
Rat protein sequence database
Cellular localization
SAGA complex,cytosol,
Tissue expression
Expressed in brain at low level.
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