Molecular weight (DA)
27kD
Immunogen
The antiserum was produced against synthesized peptide derived from human CBLN4. AA range:141-190
Specificity
Cerebellin 4 Polyclonal Antibody detects endogenous levels of Cerebellin 4 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a member of a family of small secreted proteins containing C1Q domains. Members of this family are involved in regulation of neurexin signalling during synapse development. The mouse homolog of the protein encoded by this gene competes with netrin to bind to the deleted in colorectal cancer receptor. [provided by RefSeq, Aug 2012],
Function
function:May be involved in synaptic functions in the CNS. Can enable ER export and secretion of CBLN3.,similarity:Contains 1 C1q domain.,subunit:Homohexamer; disulfide-linked homotrimers. The trimers are assembled via the globular C1q domains. The trimers associate via N-terminal cysteine residues to form disulfide-linked hexamers. May interact with CBLN1, CBLN2 and CBLN3.,
Protein name
Cerebellin-4
Abbreviation
Cerebellin 4
Other name
CBLN4; CBLNL1; Cerebellin-4; Cerebellin-like glycoprotein 1
Human protein sequence Database
Q9NTU7
Mouse protein sequence database
Q8BME9
Rat protein sequence database
Cellular localization
Secreted . Cell junction, synapse . Detected at GABAergic synapses. .
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