Molecular weight (DA)
145kD
Immunogen
Synthesized peptide derived from Neurocan . at AA range: 370-450
Specificity
Neurocan Polyclonal Antibody detects endogenous levels of Neurocan protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
Neurocan is a chondroitin sulfate proteoglycan thought to be involved in the modulation of cell adhesion and migration.[supplied by OMIM, Jul 2002],
Function
function:May modulate neuronal adhesion and neurite growth during development by binding to neural cell adhesion molecules (NG-CAM and N-CAM). Chondroitin sulfate proteoglycan; binds to hyaluronic acid.,online information:Neurocan,similarity:Belongs to the aggrecan/versican proteoglycan family.,similarity:Contains 1 C-type lectin domain.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,similarity:Contains 1 Sushi (CCP/SCR) domain.,similarity:Contains 2 EGF-like domains.,similarity:Contains 2 Link domains.,tissue specificity:Brain.,
Protein name
Neurocan core protein
Other name
NCAN; CSPG3; NEUR; Neurocan core protein; Chondroitin sulfate proteoglycan 3
Human protein sequence Database
O14594
Mouse protein sequence database
P55066
Rat protein sequence database
Cellular localization
Secreted .
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