Molecular weight (DA)
35kD
Immunogen
The antiserum was produced against synthesized peptide derived from human NPDC1. AA range:189-238
Specificity
NPDC-1 Polyclonal Antibody detects endogenous levels of NPDC-1 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:Suppresses oncogenic transformation in neural and non-neural cells and down-regulates neural cell proliferation. Might be involved in transcriptional regulation.,similarity:Belongs to the NPDC1/cab-1 family.,tissue specificity:Strongly expressed in adult brain; especially in hippocampus, frontal lobe and temporal lobe.,
Function
function:Suppresses oncogenic transformation in neural and non-neural cells and down-regulates neural cell proliferation. Might be involved in transcriptional regulation.,similarity:Belongs to the NPDC1/cab-1 family.,tissue specificity:Strongly expressed in adult brain; especially in hippocampus, frontal lobe and temporal lobe.,
Protein name
Neural proliferation differentiation and control protein 1
Other name
NPDC1; Neural proliferation differentiation and control protein 1; NPDC-1
Human protein sequence Database
Q9NQX5
Mouse protein sequence database
Q64322
Rat protein sequence database
Cellular localization
Membrane ; Single-pass membrane protein .
Tissue expression
Strongly expressed in adult brain; especially in hippocampus, frontal lobe and temporal lobe.
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