Immunogen
The antiserum was produced against synthesized peptide derived from human SCFD1. AA range:533-582
Specificity
SCFD1 Polyclonal Antibody detects endogenous levels of SCFD1 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:Involved in vesicular transport between the endoplasmic reticulum and the Golgi.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the STXBP/unc-18/SEC1 family.,subunit:Binds STX5A.,
Function
function:Involved in vesicular transport between the endoplasmic reticulum and the Golgi.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the STXBP/unc-18/SEC1 family.,subunit:Binds STX5A.,
Protein name
Sec1 family domain-containing protein 1
Other name
SCFD1; C14orf163; KIAA0917; STXBP1L2; FKSG23; Sec1 family domain-containing protein 1; SLY1 homolog; Sly1p; Syntaxin-binding protein 1-like 2
Human protein sequence Database
Q8WVM8
Mouse protein sequence database
Q8BRF7
Rat protein sequence database
Q62991
Cellular localization
Cytoplasm . Endoplasmic reticulum membrane ; Peripheral membrane protein . Golgi apparatus, Golgi stack membrane ; Peripheral membrane protein .
Tissue expression
Brain,Epithelium,Heart,Liver,Lymph,Pituitary,Placenta,Platelet,Umbilical co