Immunogen
The antiserum was produced against synthesized peptide derived from human GPR123. AA range:201-250
Specificity
GPR123 Polyclonal Antibody detects endogenous levels of GPR123 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a protein that belongs to the adhesion family of G-protein-coupled receptors. Members of this family function in several sensory systems and regulate blood pressure, immune responses, food intake and development. A similar protein in rodents is thought to play a role in in the regulation of neuronal signaling pathways. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Mar 2014],
Function
function:Orphan receptor.,similarity:Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.,
Protein name
Probable G-protein coupled receptor 123
Other name
GPR123; KIAA1828; Probable G-protein coupled receptor 123
Human protein sequence Database
Q86SQ6
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Membrane ; Multi-pass membrane protein .
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