Molecular weight (DA)
38kD
Immunogen
The antiserum was produced against synthesized peptide derived from human FFAR3. AA range:11-60
Specificity
GPR41 Polyclonal Antibody detects endogenous levels of GPR41 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:Receptor for short chain fatty acids through a G(i)-protein-mediated inhibition of adenylyl cyclase and elevation of intracellular calcium. The rank order of potency for agonists of this receptor is propionate = pentanoate = butyrate > acetate > formate.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Highest level in adipose tissue, and lower expression across all tissues tested.,
Function
function:Receptor for short chain fatty acids through a G(i)-protein-mediated inhibition of adenylyl cyclase and elevation of intracellular calcium. The rank order of potency for agonists of this receptor is propionate = pentanoate = butyrate > acetate > formate.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Highest level in adipose tissue, and lower expression across all tissues tested.,
Protein name
Free fatty acid receptor 3
Other name
FFAR3; GPR41; Free fatty acid receptor 3; G-protein coupled receptor 41
Human protein sequence Database
O14843
Mouse protein sequence database
Q3UFD7
Rat protein sequence database
Cellular localization
Cell membrane ; Multi-pass membrane protein .
Tissue expression
Highest level in adipose tissue, and lower expression across all tissues tested. Expressed in sympathetic ganglia.
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