Molecular weight (DA)
76kD
Immunogen
The antiserum was produced against synthesized peptide derived from human LRP10. AA range:204-253
Specificity
LRP10 Polyclonal Antibody detects endogenous levels of LRP10 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/10000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a low density lipoprotein receptor family protein. A similar protein in mouse is thought to play a role in the uptake of apolipoprotein E-containing lipoproteins. [provided by RefSeq, Jul 2016],
Function
function:Probable receptor, which is involved in the internalization of lipophilic molecules and/or signal transduction. May be involved in the uptake of lipoprotein APOE in liver.,sequence caution:Chimera.,similarity:Belongs to the LDLR family.,similarity:Contains 2 CUB domains.,similarity:Contains 4 LDL-receptor class A domains.,tissue specificity:Expressed in blood leukocyte, lung, placenta, small intestine, liver, kidney, spleen, thymus, colon, skeletal muscle and heart.,
Protein name
Low-density lipoprotein receptor-related protein 10
Other name
LRP10; MSTP087; SP220; Low-density lipoprotein receptor-related protein 10; LRP-10
Human protein sequence Database
Q7Z4F1
Mouse protein sequence database
Q7TQH7
Rat protein sequence database
Cellular localization
Membrane ; Single-pass type I membrane protein . Membrane, coated pit .
Tissue expression
Expressed in blood leukocyte, lung, placenta, small intestine, liver, kidney, spleen, thymus, colon, skeletal muscle and heart.