Molecular weight (DA)
33kD
Immunogen
The antiserum was produced against synthesized peptide derived from human MRGX4. AA range:271-320
Specificity
MRGX4 Polyclonal Antibody detects endogenous levels of MRGX4 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins.,similarity:Belongs to the G-protein coupled receptor 1 family. Mas subfamily.,tissue specificity:Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons.,
Function
function:Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins.,similarity:Belongs to the G-protein coupled receptor 1 family. Mas subfamily.,tissue specificity:Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons.,
Protein name
Mas-related G-protein coupled receptor member X4
Other name
MRGPRX4; MRGX4; SNSR5; SNSR6; Mas-related G-protein coupled receptor member X4; Sensory neuron-specific G-protein coupled receptor 5/6
Human protein sequence Database
Q96LA9
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Cell membrane; Multi-pass membrane protein.
Tissue expression
Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons.
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