Molecular weight (DA)
35kD
Immunogen
The antiserum was produced against synthesized peptide derived from human OR11H1/11H2/11H12. AA range:277-326
Specificity
Olfactory receptor 11H1/11H2/11H12 Polyclonal Antibody detects endogenous levels of Olfactory receptor 11H1/11H2/11H12 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008],
Function
caution:It is uncertain whether Met-1 or Met-12 is the initiator.,function:Odorant receptor .,similarity:Belongs to the G-protein coupled receptor 1 family.,
Protein name
Olfactory receptor 11H12
Abbreviation
Olfactory receptor 11H1/11H2/11H12
Other name
OR11H1; Olfactory receptor 11H1; Olfactory receptor OR22-1; OR11H2; C14orf15; OR11H2P; Olfactory receptor 11H2; Olfactory receptor OR14-1; OR11H12; Olfactory receptor 11H12Q6IEX0
Fields
>>Olfactory transduction
Human gene ID
81061/440153
Human protein sequence Database
Q8NG94/Q8NH07/B2RN74/Q6IEX0
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Cell membrane; Multi-pass membrane protein.
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