Molecular weight (DA)
48kD
Immunogen
The antiserum was produced against synthesized peptide derived from human SCTR. AA range:100-149
Specificity
Secretin Receptor Polyclonal Antibody detects endogenous levels of Secretin Receptor protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
secretin receptor(SCTR) Homo sapiens The protein encoded by this gene is a G protein-coupled receptor and belongs to the glucagon-VIP-secretin receptor family. It binds secretin which is the most potent regulator of pancreatic bicarbonate, electrolyte and volume secretion. Secretin and its receptor are suggested to be involved in pancreatic cancer and autism. [provided by RefSeq, Jul 2008],
Function
function:This is a receptor for secretin. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.,similarity:Belongs to the G-protein coupled receptor 2 family.,
Protein name
Secretin receptor
Abbreviation
Secretin Receptor
Other name
SCTR; Secretin receptor; SCT-R
Fields
>>Neuroactive ligand-receptor interaction;>>Pancreatic secretion;>>Bile secretion
Human protein sequence Database
P47872
Mouse protein sequence database
Q5FWI2
Rat protein sequence database
Cellular localization
Cell membrane ; Multi-pass membrane protein .
Tissue expression
Brain,Kidney,Lung,Pancreas,