Immunogen
Purified recombinant fragment of CD37 expressed in E. Coli.
Specificity
CD37 Monoclonal Antibody detects endogenous levels of CD37 protein.
Formulation
Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.
Dilution rate
Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Purification process (Immunogen)
Affinity purification
Background
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It may play a role in T-cell-B-cell interactions. Alternate splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],
Function
similarity:Belongs to the tetraspanin (TM4SF) family.,tissue specificity:B-lymphocytes.,
Protein name
Leukocyte antigen CD37
Other name
CD37; TSPAN26; Leukocyte antigen CD37; Tetraspanin-26; Tspan-26; CD antigen CD37
Fields
>>Hematopoietic cell lineage
Human protein sequence Database
P11049
Mouse protein sequence database
Q61470
Rat protein sequence database
Cellular localization
Membrane; Multi-pass membrane protein.
Tissue expression
B-lymphocytes.
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