Molecular weight (DA)
没有WB，所以WB没有写分子量
Immunogen
Synthetic peptide from human protein at AA range: 100-160
Specificity
The antibody detects endogenous CD80
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
IHC-p 1:50-200, ELISA 1:10000-20000. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy. [provided by RefSeq, Aug 2011],
Function
function:Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28 or CTLA-4 to this receptor.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subunit:Interacts with adenovirus subgroup B fiber proteins and acts as a receptor for these viruses.,tissue specificity:Expressed on activated B-cells, macrophages and dendritic cells.,
Gene Name
CD80 CD28LG CD28LG1 LAB7
Protein name
T-lymphocyte activation antigen CD80 (Activation B7-1 antigen) (BB1) (CTLA-4 counter-receptor B7.1) (B7) (CD antigen CD80)
Other name
T-lymphocyte activation antigen CD80 (Activation B7-1 antigen;BB1;CTLA-4 counter-receptor B7.1;B7;CD antigen CD80)
Fields
>>Cell adhesion molecules;>>Toll-like receptor signaling pathway;>>Intestinal immune network for IgA production;>>Type I diabetes mellitus;>>Autoimmune thyroid disease;>>Systemic lupus erythematosus;>>Rheumatoid arthritis;>>Allograft rejection;>>Graft-versus-host disease;>>Viral myocarditis
Human protein sequence Database
P33681
Mouse protein sequence database
Q00609
Rat protein sequence database
Cellular localization
Membrane; Single-pass type I membrane protein.
Tissue expression
Expressed on activated B-cells, macrophages and dendritic cells.
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