Molecular weight (DA)
36kD
Immunogen
The antiserum was produced against synthesized peptide derived from human MAST4. AA range:251-300
Specificity
MAST4 Polyclonal Antibody detects endogenous levels of MAST4 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a member of the microtubule-associated serine/threonine protein kinases. The proteins in this family contain a domain that gives the kinase the ability to determine its own scaffold to control the effects of their kinase activities. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2014],
Function
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,cofactor:Magnesium.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.,similarity:Contains 1 AGC-kinase C-terminal domain.,similarity:Contains 1 PDZ (DHR) domain.,similarity:Contains 1 protein kinase domain.,tissue specificity:Highly expressed in most normal human tissues, with an exception of in testis, small intestine, colon and peripheral blood leukocyte.,
Protein name
Microtubule-associated serine/threonine-protein kinase 4
Other name
MAST4; KIAA0303; Microtubule-associated serine/threonine-protein kinase 4
Human protein sequence Database
O15021
Mouse protein sequence database
Q811L6
Rat protein sequence database
Cellular localization
Cytoplasm .
Tissue expression
Highly expressed in most normal human tissues, with an exception of in testis, small intestine, colon and peripheral blood leukocyte.
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