Molecular weight (DA)
80kD
Immunogen
The antiserum was produced against synthesized peptide derived from human PHACTR4. AA range:363-412
Specificity
PHACTR4 Polyclonal Antibody detects endogenous levels of PHACTR4 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a member of the phosphatase and actin regulator (PHACTR) family. Other PHACTR family members have been shown to inhibit protein phosphatase 1 (PP1) activity, and the homolog of this gene in the mouse has been shown to interact with actin and PP1. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
Function
PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the phosphatase and actin regulator family.,similarity:Contains 3 RPEL repeats.,subunit:Binds PPP1CA and actin.,
Protein name
Phosphatase and actin regulator 4
Other name
PHACTR4; Phosphatase and actin regulator 4
Human protein sequence Database
Q8IZ21
Mouse protein sequence database
Q501J7
Rat protein sequence database
Cellular localization
Cytoplasm . Cell projection, lamellipodium .
Tissue expression
Adrenal cortex,Fetal brain,Fetal liver,Skin,Testis,
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