Molecular weight (DA)
55kD
Immunogen
The antiserum was produced against synthesized peptide derived from human PLK5. AA range:131-180
Specificity
PLK-5 Polyclonal Antibody detects endogenous levels of PLK-5 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
PLK5 (Polo Like Kinase 5) is a Protein Coding gene. Gene Ontology (GO) annotations related to PLK5 include transferase activity, transferring phosphorus-containing groups and protein kinase activity. An important paralog of PLK5 is PLK4.
Protein name
Inactive serine/threonine-protein kinase PLK5
Other name
PLK5; PLK5P; FG060302; Inactive serine/threonine-protein kinase PLK5; Polo-like kinase 5; PLK-5
Human protein sequence Database
Q496M5
Mouse protein sequence database
Q4FZD7
Rat protein sequence database
Cellular localization
Nucleus, nucleolus . Cytoplasm .
Tissue expression
Expressed in the brain, neurons and glial cells. Also expressed in highly differentiated cells, such as the serous acini in the parotid gland, distal and proximal tubules of the kidney, tubules of the seminal gland, Kupffer cells and some hepatocytes in the liver, and some cells in the germinal center of lymph nodes (at protein level).
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