Immunogen
Synthesized peptide derived from human Prolactin
Specificity
This antibody detects endogenous levels of human Prolactin. Heat-induced epitope retrieval (HIER) TRIS-EDTA of pH8.0 was highly recommended as antigen repair method in paraffin section
Source
Mouse, Monoclonal/IgG1, Kappa
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
IHC-p 1:100-500. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Background
This gene encodes the anterior pituitary hormone prolactin. This secreted hormone is a growth regulator for many tissues, including cells of the immune system. It may also play a role in cell survival by suppressing apoptosis, and it is essential for lactation. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011],
Function
function:Prolactin acts primarily on the mammary gland by promoting lactation.,online information:Prolactin entry,similarity:Belongs to the somatotropin/prolactin family.,
Protein name
Prolactin (PRL)
Fields
>>Cytokine-cytokine receptor interaction;>>Neuroactive ligand-receptor interaction;>>PI3K-Akt signaling pathway;>>JAK-STAT signaling pathway;>>Prolactin signaling pathway
Human protein sequence Database
P01236
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Secreted.
Tissue expression
Mammary gland,Pituitary,Testis,
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