Immunogen
Synthesized peptide derived from human Placental Alkaline Phosphatase(PLAP)
Specificity
This antibody detects endogenous levels of Placental Alkaline Phosphatase(PLAP) at Human
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
IHC-p 1:10. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from Cell supernatant by affinity-chromatography using specific immunogen.
Function
catalytic activity:A phosphate monoester + H(2)O = an alcohol + phosphate.,cofactor:Binds 1 magnesium ion.,cofactor:Binds 2 zinc ions.,miscellaneous:In most mammals there are four different isozymes: placental, placental-like, intestinal and tissue non-specific (liver/bone/kidney).,online information:Alkaline phosphatase entry,polymorphism:Placental ALP is highly polymorphic, there are at least three common alleles.,similarity:Belongs to the alkaline phosphatase family.,subunit:Homodimer.,
Protein name
Placental Alkaline Phosphatase(PLAP)
Other name
Alkaline phosphatase, placental type (EC 3.1.3.1;Alkaline phosphatase Regan isozyme;Placental alkaline phosphatase 1;PLAP-1)
Fields
>>Thiamine metabolism;>>Folate biosynthesis;>>Metabolic pathways;>>Biosynthesis of cofactors
Human protein sequence Database
P05187
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Cell membrane; Lipid-anchor, GPI-anchor .
Tissue expression
Detected in placenta (at protein level).
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