Molecular weight (DA)
36kD
Immunogen
The antiserum was produced against synthesized peptide derived from human ALX3. AA range:171-220
Specificity
ALX3 Polyclonal Antibody detects endogenous levels of ALX3 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a nuclear protein with a homeobox DNA-binding domain that functions as a transcriptional regulator involved in cell-type differentiation and development. Preferential methylation of this gene's promoter is associated with advanced-stage neuroblastoma tumors. [provided by RefSeq, Jul 2008],
Function
function:Transcriptional regulator with a possible role in patterning of mesoderm during development.,similarity:Belongs to the paired homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,
Protein name
Homeobox protein aristaless-like 3
Other name
ALX3; Homeobox protein aristaless-like 3; Proline-rich transcription factor ALX3
Human protein sequence Database
O95076
Mouse protein sequence database
O70137
Rat protein sequence database
Cellular localization
Nucleus .
Tissue expression
Brain,Neuroblastoma,
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