Molecular weight (DA)
38kD
Immunogen
The antiserum was produced against synthesized peptide derived from human HOXB2. AA range:41-90
Specificity
HoxB2 Polyclonal Antibody detects endogenous levels of HoxB2 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with pancreatic cancer. [provided by RefSeq, Jul 2008],
Function
developmental stage:Expressed in whole embryos and fetuses at 5-9 weeks from conception.,function:Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.,similarity:Belongs to the Antp homeobox family. Proboscipedia subfamily.,similarity:Contains 1 homeobox DNA-binding domain.,
Protein name
Homeobox protein Hox-B2
Other name
HOXB2; HOX2H; Homeobox protein Hox-B2; Homeobox protein Hox-2.8; Homeobox protein Hox-2H; K8
Human protein sequence Database
P14652
Mouse protein sequence database
P0C1T1
Rat protein sequence database
Cellular localization
Nucleus.
Tissue expression
Leukemia,Placenta,
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