Immunogen
The antiserum was produced against synthesized peptide derived from human IRX3. AA range:271-320
Specificity
IRX3 Polyclonal Antibody detects endogenous levels of IRX3 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
IHC: 1/100 - 1/300. ELISA: 1/20000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
IRX3 is a member of the Iroquois homeobox gene family (see IRX1; MIM 606197) and plays a role in an early step of neural development (Bellefroid et al., 1998 [PubMed 9427753]). Members of this family appear to play multiple roles during pattern formation of vertebrate embryos (Lewis et al., 1999 [PubMed 10370142]).[supplied by OMIM, Aug 2009],
Function
similarity:Belongs to the TALE/IRO homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,
Protein name
Iroquois-class homeodomain protein IRX-3
Other name
IRX3; IRXB1; Iroquois-class homeodomain protein IRX-3; Homeodomain protein IRXB1; Iroquois homeobox protein 3
Human protein sequence Database
P78415
Mouse protein sequence database
P81067
Rat protein sequence database
Cellular localization
Nucleus .
Tissue expression
Muscle,Skin,