Molecular weight (DA)
28kD
Immunogen
The antiserum was produced against synthesized peptide derived from human NKX26. AA range:91-140
Specificity
Nkx-2.6 Polyclonal Antibody detects endogenous levels of Nkx-2.6 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a homeobox-containing protein that belongs to the NK-2 homeobox family. This protein is a vertebrate homolog of Drosophila homeobox-containing protein called 'tinman', which has been shown to be essential for development of the heart-like dorsal vessel. In conjunction with related gene, NKX2-5, this gene may play a role in both pharyngeal and cardiac embryonic development. Mutations in this gene are associated with persistent truncus arteriosus.[provided by RefSeq, Aug 2011],
Protein name
Homeobox protein Nkx-2.6
Other name
NKX2-6; NKX2F; Homeobox protein Nkx-2.6; Homeobox protein NK-2 homolog F
Human protein sequence Database
A6NCS4
Mouse protein sequence database
P43688
Rat protein sequence database
Cellular localization
Nucleus .