Molecular weight (DA)
34kD
Immunogen
The antiserum was produced against synthesized peptide derived from human PITX1. AA range:121-170
Specificity
Pitx1 Polyclonal Antibody detects endogenous levels of Pitx1 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/20000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. Members of this family are involved in organ development and left-right asymmetry. This protein acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin. [provided by RefSeq, Jul 2008],
Function
function:May play a role in the development of anterior structures, and in particular, the brain and facies and in specifying the identity or structure of hindlimb.,similarity:Belongs to the paired homeobox family. Bicoid subfamily.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 1 OAR domain.,
Protein name
Pituitary homeobox 1
Other name
PITX1; BFT; PTX1; Pituitary homeobox 1; Hindlimb-expressed homeobox protein backfoot; Homeobox protein PITX1; Paired-like homeodomain transcription factor 1
Human protein sequence Database
P78337
Mouse protein sequence database
P70314
Rat protein sequence database
Q99NA7
Cellular localization
Nucleus.
Tissue expression
Embryo,Epithelium,Pancreas,Placenta,
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