Molecular weight (DA)
24kD
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human FGF16. AA range:141-190
Specificity
FGF-16 Polyclonal Antibody detects endogenous levels of FGF-16 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a member of a family of proteins that are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene is expressed in cardiac cells and is required for proper heart development. Mutation in this gene was also observed in individuals with metacarpal 4-5 fusion. [provided by RefSeq, Mar 2014],
Function
function:Induces hepatocellular proliferation. Has no biological effect on the heart.,similarity:Belongs to the heparin-binding growth factors family.,
Protein name
Fibroblast growth factor 16
Other name
FGF16; Fibroblast growth factor 16; FGF-16
Fields
>>MAPK signaling pathway;>>Ras signaling pathway;>>Rap1 signaling pathway;>>Calcium signaling pathway;>>PI3K-Akt signaling pathway;>>Regulation of actin cytoskeleton;>>Pathways in cancer;>>Chemical carcinogenesis - receptor activation;>>Melanoma;>>Breast cancer;>>Gastric cancer
Human protein sequence Database
O43320
Mouse protein sequence database
Q9ESL8
Rat protein sequence database
O54769
Cellular localization
Secreted .
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