Molecular weight (DA)
25kD
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human PRL. AA range:131-180
Specificity
Prolactin Polyclonal Antibody detects endogenous levels of Prolactin protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/20000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes the anterior pituitary hormone prolactin. This secreted hormone is a growth regulator for many tissues, including cells of the immune system. It may also play a role in cell survival by suppressing apoptosis, and it is essential for lactation. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011],
Function
function:Prolactin acts primarily on the mammary gland by promoting lactation.,online information:Prolactin entry,similarity:Belongs to the somatotropin/prolactin family.,
Other name
PRL; Prolactin; PRL
Fields
>>Cytokine-cytokine receptor interaction;>>Neuroactive ligand-receptor interaction;>>PI3K-Akt signaling pathway;>>JAK-STAT signaling pathway;>>Prolactin signaling pathway
Human protein sequence Database
P01236
Mouse protein sequence database
P06879
Rat protein sequence database
Cellular localization
Secreted.
Tissue expression
Mammary gland,Pituitary,Testis,
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